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AMP-ACTIVATED PROTEIN KINASES
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DeCS
Descriptor
English
:
AMP-Activated Protein Kinases
Descriptor
Spanish
:
Proteínas Quinasas Activadas por AMP
Descriptor
Portuguese
:
Proteínas Quinases Ativadas por AMP
Tree Number:
D08.811.913.696.620.682.700.085
D12.644.360.062
D12.776.476.062
Definition
English
:
Intracellular signaling
protein kinases
that play a signaling role in the regulation of cellular
energy metabolism
. Their activity largely depends upon the
concentration
of cellular AMP which is increased under conditions of low
energy
or metabolic stress.
AMP-activated protein kinases
modify
enzymes
involved in
LIPID METABOLISM
, which in turn provide
substrates
needed to convert AMP into ATP.
History Note
English
:
2009(1980)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53121
Unique Identifier:
D055372
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS